UniCarb-DB: a database resource for glycomic discovery
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چکیده
منابع مشابه
UniCarb-DB: a database resource for glycomic discovery
UNLABELLED Glycosylation is one of the most important post-translational modifications of proteins, known to be involved in pathogen recognition, innate immune response and protection of epithelial membranes. However, when compared to the tools and databases available for the processing of high-throughput proteomic data, the glycomic domain is severely lacking. While tools to assist the analysi...
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UniCarb-DB is an experimental database consisting of structural information of O-linked and N-linked oligosaccharides and associated LC-MS/MS fragmentation data. This report illustrates how the database can be useful for future software development for the interpretation of glycomic mass spectrometric data. The information about rich fragmentation spectra generated for O-linked oligosaccharides...
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The rapid pace at which genomic and proteomic data is being generated necessitates the development of tools and resources for managing data that allow integration of information from disparate sources. The Human Protein Reference Database (http://www.hprd.org) is a web-based resource based on open source technologies for protein information about several aspects of human proteins including prot...
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Gastrointestinal (GI) cancer is the most common group of malignancies and many of its types are among the most deadly. Various glycoconjugates have been used in clinical practice as serum biomarker for several GI tumors, however, with limited diagnose application. Despite the good accessibility by endoscopy of many GI organs, the lack of reliable serum biomarkers often leads to late diagnosis o...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2011
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btr137